Polynucleotides are highly purified DNA fragments used in regenerative medicine to support the skin’s natural repair processes. They help improve skin texture, elasticity, and hydration, and are suitable both for preventing signs of ageing and for enhancing overall skin quality.
Rejuran Polynucleotides
Rejuran® is a regenerative injectable treatment from South Korea containing highly purified polynucleotides derived from salmon DNA. Rejuran® supports the skin’s natural ability to repair itself and helps improve overall skin quality.
Rejuran is suitable for:
- treating acne scars and superficial scars
- reducing fine lines and wrinkles
- improving enlarged pores and uneven skin texture
- enhancing skin elasticity and firmness
- refreshing dull and tired-looking skin
- improving the quality of the delicate skin around the eyes
Different Rejuran formulations have been developed for specific areas and skin concerns, making it possible to select the most suitable option for each patient’s individual needs. For example, there are separate formulations for the eye area, for improving overall facial skin quality, and for treating acne scars and other scarred areas.
Rejuran products are based on patented DOT™ technology, or DNA Optimizing Technology, which is used in the production of highly purified polynucleotides.
What Are the Benefits of Polynucleotides?
Polynucleotides stimulate the skin’s natural repair processes by hydrating the skin, supporting cell renewal, and promoting collagen production. This helps the skin regain elasticity and fullness.
Polynucleotides also have antioxidant and anti-inflammatory properties.
Polynucleotides and the Eye Area
The eye area is often one of the first places where signs of ageing appear, including wrinkles and skin laxity. This is because the skin around the eyes is among the thinnest areas of the face and is therefore more prone to wrinkles, dryness, and other signs of ageing.
The skin around the eyes also contains relatively few sebaceous glands, which means that it is not naturally well hydrated. In addition, the eye area reacts quickly to fatigue, stress, and lack of sleep, which may result in dark circles, puffiness, and wrinkles.
Using polynucleotides around the eyes can help improve skin elasticity, increase hydration, and reduce fine lines.
How Is the Procedure Performed?
The product is injected into the dermal layer of the skin using very fine needles. The procedure is generally well tolerated, and a numbing cream can be applied if desired.
After the procedure, small papules may appear on the surface of the skin. These usually remain visible for approximately one to three days. Makeup may be applied from the following day.
We recommend avoiding saunas, intensive exercise, and hot baths for 24–48 hours after the procedure.
A course of three to four treatments at intervals of 15–30 days is recommended.
Who Is the Treatment Not Suitable For?
The procedure is not suitable for:
- people with a fish allergy
- people with autoimmune diseases
- people prone to keloid scarring
- pregnant women
- breastfeeding women
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